San Francisco (5-6) at Buffalo (9-2) Sunday, 8:20 p.m. EST, NBC BetMGM NFL odds: Bills by 7. Series record: Bills lead 7-6. Against the spread: 49ers 4-7, Bills 7-4. Last meeting: Bills beat 49ers 34-24 on Dec. 7, 2020, at Glendale, Arizona.
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